Table 4.

ORs and 95% CIs for the Association of CLD With Mechanical Ventilation From Epoch One (Day of Birth) Through Epoch Three (Days Four to Seven)

Epoch 0Epoch 1Epoch 2Epoch 3
Mechanical ventilation, d of birth13.4 (5.9, 30.7)3.2 (1.2, 8.4)3.7 (1.4, 9.8)
Mechanical ventilation, d 1–39.6 (4.2, 22.0)3.6 (1.4, 9.4)
Mechanical ventilation, d 4–76.3 (3.2, 12.5)
Boston6.0 (2.7, 13.0)1.8 (.8, 4.2)2.0 (.9, 4.8)2.3 (.95, 5.7)
Boston (among mechanicaly ventilated) 1.5 (.6, 4.0)1.5 (.5, 4.2)2.6 (.8, 7.9)4.4 (.9, 21.1)
  • * All models are adjusted for epoch 0 (pre/perinatal variables), including: gestational age <26 weeks, gestational age 26 to 28 weeks, magnesium sulfate infusion during labor, neonatal thyroxine level <5.3 μg/dL, and antenatal glucocorticoid treatment. Bold indicates values that achieved statistical significance (P < .05).

     The models limited to the population of mechanically ventilated infants are adjusted for the variables listed in Table 5rather than the summary mechanical ventilation variable for each epoch.