Table 3.

Factors Considered Candidates for Multivariate Analysis, by Epoch

Prenatal/Perinatal EpochEach Subsequent Epoch
(Day of Birth, Postnatal Days 1–3, and Postnatal Days 4–7)
Diagnoses Physiologic MeasuresTreatments
Gestational age
Birth weight
Sex
Race
Birth weight z score
Initiator of preterm delivery
 (PROM, PTL, toxemia)
Singleton vs multiple gestation
Duration of labor
Duration of membrane rupture
Antenatal glucocorticoid Rx
Antenatal magnesium sulfate Rx
Chorioamnionitis
Fetal vasculitis
Thyroxine level
Pneumothorax
PIE
PDA
Lowest mean BP
Highest WBC
Lowest hematocrit
Lowest platelet count
Highest dextrostick
Highest BUN
Highest Cr
Lowest Pao2
Lowest Paco2
Highest Paco2
Lowest pH

Weight change
Mode of ventilation
Ventilator settings
  Highest MAwP
Lowest MAwP
Highest PIP
Lowest PIP
Mode PEEP
Highest ventilator rate
Highest Fio2
Insulin
Pressors
Narcotic sedation
Volume expanders
Total fluids
Crystalloid fluids
Lasix
Indomethacin
Surfactant
  • Rx indicates treatment; BP, blood pressure; Cr, creatinine; BUN, blood urea nitrogen; PIE, pulmonary interstial emphysema; PROM, premature rupture of membranes; PTL, preterm labor; WBC, white blood count.

  • * Each considered as a composite variable reflecting the diagnosis any time in the first 7 postnatal days.