Table 7.

Summary of Evidence Tables for Development of AVN*

Age at Initial
Referral (Arc)
AVN After Orthopaedic
Referral Rate per 1000 Referred Infants
Sample Size
Average
(SD)
Sample Size
Total
No. of
Arms
Unweighted
Average
(SD)
Weighted
Average
(SD)
Meta-analytic
Average (SD)
Younger than 2 mo (5, 12+ → 31)16.6 (35)6.4 (23)13.5 (24)514 (922)760617
Without outliers§ 2.5 (5.9)1.5 (1.4)2.5 (9.5)447 (907)
Older than 2 mo (20, 29, 30+ → 31)116 (70)54 (49)109 (88)1158 (1885)92707
  • * AVN indicates avascular necrosis. See Evidence Tables 7 and 8.

  • Arc refers to the influence diagram (see Fig. 2).

  • Weighted estimates computed by pooling the numerators and denominators of the target arms.

  • § Outliers are target article 83 (81/1000), target article 84 (123), and target article 60 (43).