Table 2.

The First Occurrence of Isolated CL ± CP and CP in the Previous Hungarian RCT and the PCS of Periconceptional Folic Acid-containing (.8 mg) Multivitamin Supplementation

StudyIsolated Orofacial CleftsSupplemented GroupUnsupplemented GroupOR95% CI
NNumberPer 1000NNumberPer 1000
RCT247141.6223902.841.94.41 –9.09
PCSCL ± CP30172.6634312.581.14.20 –6.57
Together548861.0958214.691.59.48 –5.30
RCT24710.0023912.84.19.01 –4.03
PCSCP30181.3334321.291.14.12 –10.94
Together54891.1858233.52.35.05 –2.40
  • N indicates number of informative offspring evaluated.