Table 5.

CF Infants Before LRI: Baseline Pulmonary Function and Viral Antibody Titers

CF URI-Only (n = 17)CF LRI
(n = 13)
Pulmonary function
 V′maxFRC/length
  (mL/sec/cm)
2.97  ± 1.212.91  ± 1.24
 FRC/length (mL/cm)2.67  ± 0.582.45  ± 0.73
 Respiratory rate (breaths/min)39  ± 1346  ± 21
 Spo2 (%)97  ± 196  ± 2
Antibody titers (GMT)
 Influenza A virus
  H1N12.57  ± 2.841.38  ± 1.26
  H3N23.25  ± 1.532.63  ± 2.23
 Influenza B virus0.65  ± 0.441.00  ± 1.33
 Parainfluenza virus type 33.56  ± 3.745.50  ± 3.50
 Respiratory syncytial virus
  type A
3.00  ± 1.514.83  ± 2.69*
 Adenovirus9.38  ± 2.728.81  ± 2.56
  • Data are expressed as mean ± standard deviation (SD) values.

    Abbreviations: GMT, geometric mean titer in log 2; CF URI-only, cystic fibrosis infants who had only upper respiratory tract infections during the respiratory virus season; CF LRI, cystic fibrosis infants who had at least one lower respiratory tract infection during the respiratory virus season.

  • * P < .05.

  • Enzyme-linked immunosorbent assay to hexon.