Table 2.

Respiratory Tract Illness and Viral Infection

Control (n = 28)CF (n = 30)
Respiratory tract illnesses
 Average number of reported illnesses5 ± 35 ± 3
 Number of infants with URI only24 /28 (86%)17 /30 (57%)
 Number of infants with URI and ≥1 LRI4 /28 (14%)13 /30 (43%)
 Number of infants hospitalized with LRI*0 /287 /30 (23%)
Viral infection
 RSV19 /28 (68%)7 /30 (23%)§
 Influenza virus A and B15 /28 (54%)9 /30 (30%)
 Parainfluenza virus type 311 /28 (39%)5 /30 (17%)
 Adenovirus9 /28 (32%)5 /30 (17%)
 Picornavirus12 /28 (43%)8 /30 (27%)
 Total number of positive cultures/total number of cultures40 /141 (28%)26 /150 (17%)
  • Data are expressed as percentages or as mean ± standard deviation (SD) values.

    Abbreviations: URI, upper respiratory tract infection; LRI, lower respiratory tract infection.

  • * Respiratory virus isolates by culture: 3 RSV, 1 Picornavirus.

  • Infection is defined as a ≥4-fold antibody rise and/or positive culture.

  • P < .05;

  • § P < .01;

  • P < .07, all compared with controls.