Table 1.

CF Infants and Controls at Entry Into the Study

Control (n = 28)CF (n = 30)
Family/social/medical history
 Family history of asthma11/28 (39%) 16/29 (55%)
 ETS exposure7/28 (25%) 10/30 (33%)
 Day care8/26 (31%)  3/30 (10%)*
 Number of children in home (0–18 y)2  ± 12  ± 1
 SES score49  ± 1140  ± 16
Anthropometric measurements
 Age (mo)10  ± 610  ± 6
 Sex (M:F)15:1320:10
 Length (cm)73  ± 968  ± 11
 Weight (kg)9.25  ± 2.237.39  ± 2.88
 Weight/length percentile (%)54  ± 2829  ± 24
 Weight/length Z score0.23  ± 1.0−0.82  ± 1.0
Pulmonary function
 FRC/length (mL/cm)2.32  ± 0.692.58  ± 0.64
 V′maxFRC/length (mL/sec/cm)3.76  ± 1.862.94  ± 1.20*
 Respiratory rate (breaths/min)30  ± 642  ± 17
 Spo2 (%)97  ± 196  ± 2
Antibody titers (GMT)
 Influenza A virus
  H1N13.34  ± 2.32.98  ± 1.9
  H3N21.58  ± 1.82.04  ± 2.3
 Influenza B virus0.74  ± 0.40.80  ± 0.9
 Parainfluenza virus type 36.61  ± 2.84.39  ± 3.7*
 Respiratory syncytial virus type A4.73  ± 2.43.79  ± 2.3
 Adenovirus9.54  ± 2.69.12  ± 2.6
  • Data are expressed as percentages or as mean ± standard deviation (SD) values.

    Abbreviations: ETS, environmental tobacco smoke exposure; SES, socioeconomic score (Hollingshead); FRC, functional residual capacity. V′max FRC, maximum flow at functional residual capacity; GMT, geometric mean titer in log 2 value. All antibody titers were measured by microneutralizing antibody assay except for adenovirus, which was measured by enzyme-linked immunosorbent assay.

  • * P < .05, compared with controls;

  • P < .01, compared with controls.