TABLE 1.

Serum Immunoglobin Levels, Specific Antibody Titers, and T-Lymphocyte Proliferation

Patient 1Patient 2
Serum immunoglobin, g/L
    IgM0.69 (0.66–1.18)0.2 (0.68–1.28)
    IgG11.4 (7–12.6)12.19 (8.3–14.3)
    IgA4.03 (0.78–1.62)1.25 (1.02–1.94)
Specific antibodies to
    TetanusND0.32 (>0.17 IU/mL)
    Hib*46% inhibition0.89 (>0.15 μg/mL)
    Pneumococcus0.8 (>0.3 μg/mL)<4.0 (>15.4 IU/mL)
        Serotype 30.12 μg/mL (>0.5 μg/mL)ND
        Serotype 40.07 μg/mL (>0.7 μg/mL)ND
        Serotype 9N0.7 μg/mL (>1.4 μg/mL)ND
        Serotype 18C0.08 μg/mL (>0.8 μg/mL)ND
        Serotype 23F0 μg/mL (>0.15 μg/mL)ND
T-lymphocyte proliferation, cpm
    Phytohemagglutinin18 23019160 (>50 000)
    Candidin1257250 (>1000)
    Tuberculin4485640 (>1000)
    Tetanus toxoid67033170 (>1000)
  • Patients 1 and 2 were tested at 5 and 9 years of age, respectively. ND indicates not determined.

  • * After Hib-conjugated vaccination.

  • Vaccinated by Pneumovax 23.