APPENDIX 2.

Components of Cost-of-Disease Calculation According to Meningococcal Disease Outcome

OutcomeMedical Care for Acute Meningococcal DiseaseParents' Work LossPublic Health Response to an Isolated Case of Meningococcal DiseaseAcute, Sequela- Specific Medical CareLifetime Medical Costs of Sequelae (Rehabilitation, Prosthesis, Implant)Long-Term Residential CareSpecial EducationProductivity Loss*
Survival without sequelaeXXX
DeathXXXX
Skin scarringXXXX
Single amputationXXXXX
Multiple amputationsXXXXXX
Hearing lossXXXXX
Neurologic disabilityXXXXXX
  • * Productivity losses differ by meningococcal disease sequelae: for deaths, the cost of productivity losses was equated to the sum of lifetime labor market earnings and household production losses; for survivors with neurologic disability, losses were equated to the sum of lifetime labor market earnings only; for survivors with multiple amputations, losses were equated to the sum of 30% of lifetime labor market earnings; and for survivors with hearing loss, losses were equated to the sum of 33% of lifetime labor market earnings.