Table 3.

Results of Regression Models of Birth Weight for a Subset of 122 Infants With HIV-Positive Mother Having Data for Maternal CD4 Percent, CD8 Percent, and Malarial Parasitemia in Butare, Rwanda, 1989–1994§

Changes in Birth Weight (g) and 95% CI
Unadjusted ModelTrivariate Models Adjusted for Infant's HIV
Status, Gestational Age, and
Full Model
ln(CD4:CD8 ratio)Malaria
Infant's HIV status
 Infected−208 (−398, −18)* −140 (−307, 28)−140 (−298, 19)−91 (−231, 49)
 Not infected0000
Gestational age (wk)
 ≤37−817 (−1043, −590) −744 (−1009, −480) −777 (−1038, −516) −747 (−968, −527)
 38–39−328 (−465, −192) −329 (−480, −178) −324 (−471, −177) −243 (−371, −114)
 400000
 ≥41221 (55, 389) 174 (−22, 370)166 (−26, 358)157 (−9, 323)
Logarithm of CD4:CD8 ratio42 (−90, 174)−15 (−129, 99)28 (−66, 121)
Malarial parasitemia−153 (−364, 58)−197 (−370, −24)* −189 (−332, −45)*
  • * P ≤ .05;

  • P ≤ .01;

  • P ≤ .001.

  • § Lymphocytes were tested prenatally or within 100 days' postpartum. Of the 122 infants having data for all variables in the full model, 24 infants were infected and 98 were uninfected.

  • Model including logarithm of mother's CD4:CD8 ratio and malarial parasitemia, in addition to infant's HIV status, gestational age, maternal parity, age, cigarette-smoking, MUAC, height, hematocrit, and family income.