TABLE 3.

Prenatal Diagnosis, Pregnancy Termination, and Perinatal and Early Neonatal Mortality for Selected (Isolated) Congenital Heart Anomalies, Paris Registry of Congenital Malformations, 1983–2000

1983–19881989–19941995–2000P
N%95% CI*N%95% CI*N%95% CI*
TGA
    Prenatal diagnosis1612.51.6–38.32748.128.7–68.14072.556.1–85.40.001
    Pregnancy termination1700–19.5277.40.9–24.34000–8.80.62
    First-week mortality1618.84.0–45.6248.31.0–27.0392.60.1–13.50.04
    Perinatal mortality1723.56.8–49.92512.02.5–31.2405.00.6–16.90.02
HLHS
    Prenatal diagnosis2231.813.9–54.92982.864.2–94.22788.970.8–97.6<0.001
    Pregnancy termination2213.62.9–34.92972.452.8–87.32763.042.4–80.6<0.001
    First-week mortality1883.358.6–96.4875.034.9–96.81050.018.7–81.30.12
    Perinatal mortality1984.260.4–96.6875.034.9–96.81050.018.7–81.30.10
Coarctation of aorta
    Prenatal diagnosis600–45.92133.314.6–57.03342.425.5–60.80.03
    Pregnancy termination600–45.92100–16.13400–10.3-
    First-week mortality600–45.92100–16.13400–10.3-
    Perinatal mortality600–45.92100–16.13400–10.3-
Tetralogy of Fallot
    Prenatal diagnosis1020.02.5–55.61637.515.2–64.63369.751.3–84.40.005
    Pregnancy termination1010.00.3–44.51612.51.6–38.33400–10.30.07
    First-week mortality900–33.61300–24.73300–10.6-
    Perinatal mortality900–33.6147.10.2–33.9342.90.1–15.30.63
  • * 97.5% 1-sided CIs for cases with 0 events.

  • Test of significance for cusum linear annual trend.