TABLE 4.

Results of Univariate and Multivariate Analyses of Perinatal Risk Factors Associated With Death Before Discharge in 303 NICU-Admitted Infants

Variable (All Yes/No Unless Stated)Univariate AnalysisMultivariate Analysis (Forward Stepwise)
OR (95% CI)P ValueOR (95% CI)P Value
Intrauterine transfer1.25 (0.70–2.22).444
Medically assisted conception0.92 (0.40–2.14).859
PROM (>24 h)0.69 (0.33–1.45).335
CS vs vaginal delivery0.40 (0.22–0.74).0030.41 (0.23–0.74).003
Male gender1.17 (0.65–2.10).588
Gestation (per wk)0.36 (0.25–0.50)<.00050.35 (0.23–0.51)<.0005
BW (per 100 g)0.99 (0.99–1.00).49
Multiple1.10 (0.57–2.14).761
Air leak syndrome (<48 h)2.01 (1.02–3.98).0442.13 (1.10–4.12).024
Endotracheal ventilation1.24 (0.30–5.08).758
Days on the ventilator0.96 (0.94–0.98).0010.96 (0.95–0.98).001
Surfactant therapy1.43 (0.62–3.28).396
Minimal Fio2 <12 h0.20 (0.10–0.40)<.00050.18 (0.09–0.34)<.0005
Maximal Fio2 <12 h0.59 (0.30–1.13).114
  • PROM indicates premature rupture of membranes.