Table 7.

Meta-analytic Summary of the Effect of β2-Agonists on Physiologic Measures After Two Treatments in Outpatient Trials

Studyβ2-AgonistPlaceboMean Difference95% CI
nX ± SDnX ± SD
Respiratory Rate (breaths per minute)
Schuh1321−11.3  ± 1019−5  ± 8−6.3−12.1, −.5
Klassen1442−.7  ± 241−.4  ± 2−.3−1.1, .5
Schweich1513−1.4  ± 1712−.5  ± 12−.9−13.1, 11.3
Gadomski1821−11  ± 918−6  ± 13−5−12.2, 2.7
Gadomski1932−4  ± 832−4  ± 100−4.5, 4.5
Overall−.5−1.3, .3
Oxygen Saturation (%)
Schuh1321.8  ± .219−.8  ± 21.6.6, 2.5
Klassen1442.4  ± 441.2  ± 4.2−1.6, 2
Schweich15132.4  ± 412−.4  ± 52.8−.7, 6.3
Gadomski1821.1  ± 218.1  ± 20−1.3, 1.3
Gadomski1932−.7  ± 330−.3  ± 4−.4−2.2, 1.4
Overall1.2.8, 1.6
Heart Rate (beats per minute)
Schuh13217.8  ± 1219−6.8  ± 1714.65.3, 23.9
Klassen14423  ± 3411.9  ± 21.1   .003, 2.2
Schweich1513−13  ± 2112−15  ± 222−15.6, 19.6
Gadomski18212  ± 1618−4  ± 146−3.8, 15.8
Gadomski193211  ± 18322  ± 289−2.8, 20.8
Overall1.4.8, 2