Radioactive Compounds Requiring Prolonged Cessation of Breastfeeding

CompoundExamplesExample of ProceduresRecommended Time for Cessation of BreastfeedingComments
I-labled123I- BMIPP, -HSA, -IPPA, -MIBG, -NaI, or -HSAImaging of tumorsGreater than 3 wkEssentially need to stop breastfeeding
131I-MIBG or -NaI
Others201Tl-chlorideCardiac imaging48 h to 2 wkHalf-life 73 ha
67Ga-citrateImaging of tumors1 wk to 1 moDepends on dose
22Na, 75SeGreater than 3 wkEssentially need to stop breastfeeding
  • Use of expressed human milk recommended because of exposure via direct contact.120 BMIPP, β-methyl-p-iodophenyl-pentadecanoic acid; HSA, human serum albumin; IPPA, iodophenylpentadecanoic; MIBG, metaiodobenzylguanidine; NaI, sodium iodide.

  • a FDA-approved drug labeling.