Table 1.

Data Obtained at Baseline (Day 1) and Throughout the Study.

Physical examination including blood pressure, respiration, and temperature (daily)
Chest radiograph (days 1, 28, and as clinically indicated)
Arterial blood gases (as clinically indicated)
CBC with differential, platelet count, and reticulocytes (days 1, 3, 7, 13, 21, 28)
Serum Na+, K+, Cl, HCO3, Ca++, glucose, BUN, and creatinine (days 1, 3, 7, 13, 21, 28)
SGOT, alkaline phosphatase, bilirubin, total protein, and albumin (days 1, 3, 7, 13, 21, 28)
Serum SOD level (days 1, 3, 5, 7, 13)
Serum for anti–SOD antibodies (days 1, 28)
Urinalysis (days 1, 3, 7, 13, 21, 28)
Urine for creatinine clearance (days 7, 13, 21, 28)
Urine SOD level (days 3, 5, 7, 13)
Blood cultures (day 1 and as clinically indicated)
Tracheal aspirate cell count, cytology and SOD level (days 1, 3, 5, 7, 13 if intubated)
Cranial ultrasounds (days 1, 5, 28)
Cardiac echocardiogram (day 3 and as clinically indicated)
Opthamologic examination for ROP (day 28)