TABLE 1.

Anthropometric and Laboratory Features of Rachitic Subjects With Ichthyosis

CharacteristicCase 1Case 2Case 3Reference Range
Anthropometric data
 Weight, kg6.715.324.4
 Height, cm62.893.5115
 Weight for height, Z score0.320.821.98
 Weight for age, Z score−3.5−3.10.42
 Height for age, Z score−5−6−1.3
Serum*
 Calcium, mg/dL9.6–10.6
  Pretreatment8.96.96.8
  Posttreatment9.09.6
 Corrected calcium, mg/dL8.55.77.49.6–10.6
 Phosphorus, mg/dL2.03.93.04.3–5.4
 Alkaline phosphatase, U/L<400
  Pretreatment7073491987
  Posttreatment333
 Albumin, g/dL4.35.03.63.5–5.0
 25-Hydroxyvitamin D, ng/mL8–38
  Pretreatment<4.5<4.5
  Posttreatment6010
 1,25-Dihydroxyvitamin D, pg/mL22–67
  Pretreatment57102110
  Posttreatment200139
 Parathyroid hormone, pg/mL1.0–5.2
  Pretreatment6339173
  Posttreatment4.22231
 Urinary calcium excretion, mg/d0.5212.525–300
 Fractional absorption of calcium, %7615–60
  • * To convert values for calcium to millimoles per liter, multiply by 0.25; to convert values for phosphorus to millimoles per liter, multiply by 0.32; to convert values for 25-hydroxyvitamin D to nanomoles per liter, multiply by 2.50; to convert values for 1,25-dihydroxyvitamin D to picomoles per liter, multiply by 2.40; and to convert the values for parathyroid hormone to picomoles per liter, multiply by 0.11.

  • Serum calcium was corrected for albumin concentration by using the following formula: corrected calcium (mg/dL) = total calcium (mg/dL) + 1.2 × [4 − albumin (g/dL)].

  • As determined by 24-hour collection of urine after oral administration of Ca45 and intravenous administration of Ca47.