TABLE 2.

Predictors of Hyperbilirubinemia and Severe Hyperbilirubinemia (n = 5507)

PredictorMaximum TSB ≥20 mg/dLMaximum TSB ≥ Age-Specific AAP Criteria
OR*95% CIP ValueOR*95% CIP Value
Maternal race
White (referent)1.001.00
Black0.3620.148–0.885.0260.3460.220–0.545<.001
Asian1.3640.286–6.510.6971.2740.547–2.967.575
Latino0.6330.220–1.825.3980.6900.412–1.157.160
Other/unknown0.2280.029–1.823.1640.4440.194–1.016.055
Newborn gender
Female (referent)1.001.00
Male2.2741.058–4.886.0351.3930.977–1.987.067
Feeding type
Exclusive or partial breastfeeding2.3981.011–5.689.0471.702§1.152–2.516.008
Formula feeding (referent)1.001.00
Gestational age in weeks
35–363.3991.044–11.061.0423.0801.644–5.768<.001
372.7940.982–7.945.0542.1171.205–3.720.009
380.5440.152–1.943.3480.7380.426–1.280.280
39–40 (referent)1.001.00
40+1.1210.360–3.493.8441.0330.603–1.769.907
Birth weight1.0000.999–1.000.4081.0001.000–1.000.800
Maternal age1.0851.027–1.146.0041.0090.981–1.038.535
Access to care
Non-HFHSF (referent)1.001.00
HFHSF1.2570.540–2.930.5961.8931.236–2.900.003
Hosmer-Lemeshow goodness of fitP = 0.312P = 0.197
C statistics0.7890.687
  • * OR indicates odds ratio.

  • Wald χ2 test of OR = 1.0; CI indicates confidence interval.

  • For exclusive breastfeeding versus partial breastfeeding for risk of TSB ≥20 mg/dL (OR = 1.051; P = 0.904).

  • § For exclusive breastfeeding versus partial breastfeeding for risk of TSB ≥ age-specific AAP criteria (OR = 1.381; P = 0.135).