TABLE 5

Randomized Controlled Trials Comparing Different Antimicrobial Treatments for Acute Sinusitis

Author (Year)Age (y)Antimicrobial AgentsDurationNCured (%)Improved (%)Failed (%)Relapsed (%)Recurred (%)Jadad Score
Poachanukoon and Kitcharoensakkul (2008)121–15Amoxicillin-clavulanate (80–90 mg/kg per day)14 d72ND85ND1163
Cefditoren (4–6 mg/kg) 2 times/d14 d66ND79ND93
Simon (1999)130.5–17Erythromycin (40 mg/kg per day)14 d5096ND4ND101
Ceftibuten (9 mg/kg per day)10 d5092ND8ND12
Ceftibuten (9 mg/kg per day)15 d5092ND8ND8
Ceftibuten (9 mg/kg per day)20 d50100ND0ND8
Ficnar et al (1997)140.5–12Azithromycin (10 mg/kg per day)3 d2796ND04ND1
Azithromycin (10 mg/kg on day 1, then 5 mg/kg on days 2–5)5 d18100ND00ND
Careddu et al (1993)152–14Brodimoprim (10 mg/kg on day 1, then 5 mg/kg per day)8 d2596ND4NDND1
Amoxicillin-clavulanate (50 mg/kg per day)NS2785ND15NDND
Wald et al (1984)161–16Amoxicillin (40 mg/kg per day)10 d2781411443
Cefaclor (40 mg/kg per day)10 d2378941117
  • ND, not determined; NS, not specified.