TABLE 1.

Effects of Antibiotic Rotation on Resistant Bacillary Colonization

Control Team (N = 548)Rotation Team (N = 514)P*
Incidence of resistant colonization42 (7.7)55 (10.7).09
Mean resistant bacilli/positive patient2.46 (2.60)2.54 (2.35).88
Mean discordant bacilli/admission0.20 (1.02)0.28 (1.12).09
 Mean resistant to gentamicin§0.11 (0.69)0.12 (0.57).43
 Mean resistant to piperacillin-tazobactam§0.08 (0.49)0.13 (0.61).08
 Mean resistant to ceftazidime§0.12 (0.74)0.17 (0.76).09
  • * By Wilcoxon rank sum.

  • Indicates number (%) of infants on each team colonized with at least 1 resistant Gram-negative bacillus.

  • Indicates mean (standard deviation) number of genetically discordant, antibiotic-resistant Gram-negative bacilli isolated per admission.

  • § Indicates mean (standard deviation) number of genetically discordant Gram-negative bacilli resistant to each of the 3 rotation antibiotics, per admission.