TABLE 6.

Mean Baseline and Percentage Change From Baseline Values (SE) for Markers of Bone Metabolism and Bone Mineral Density (Patients Who Participated in the Assessment)

HFA−BDP 100–200 μgCFC−BDP+S 200–400 μgP Value
Osteocalcin
 Baseline (ng/mL)84.93 (2.129)86.03 (3.611).794
n = 168n = 58
 % change at month 123.3 (3.31)5.8 (5.99).711
n = 125n = 44
1-CTP
 Baseline (μg/L)10.20 (0.199)10.77 (0.330).141
n = 160n = 57
 % change at month 1215.8 (3.14)25.7 (5.34).112
n = 122n = 45
Urine deoxypyridinoline/ creatinine (nmol-d/nmol-c)
 Baseline22.50 (1.172)19.89 (2.056).270
n = 162n = 57
 % change at month 1233.7 (8.36)65.5 (14.09).054
n = 120n = 46
PICP
 Baseline (ng/mL)308.76 (14.877)339.31 (25.560).303
n = 156n = 55
 % change at month 1215.0 (4.26)25.7 (7.49).218
n = 116n = 41
Bone mineral density*
 Baseline (g/cm3)2.47 (0.104)2.26 (0.201)
n = 15n = 4
 % change at month 127.1 (1.36)11.0 (2.54)
n = 14n = 4
  • * Between-group comparisons were not tested for bone mineral density.