TABLE 3.

EV71 Seropositivity Rates After the Epidemic Among 1800 Children 6 to 72 Months of Age in Families With Different Numbers of Children

Number of ChildrenEV71 Seropositive Rate*Adjusted OR95% CI
114% (355)1.0
228% (857)1.51.1–2.1
331% (394)1.71.2–2.5
437% (118)2.31.4–3.8
≥538% (76)2.41.3–4.3
  • * Numbers in parentheses are total numbers of tested samples.

  • Multivariate-adjusted OR calculated using the group with 1 child per family as the reference group and adjusted by age, kindergarten attendance, residential area, and contact with HFMD/herpangina.

  • Mantel-Haenszel trend test, OR: 1.3; 95% CI: 1.2–1.4; P < .001.