Characteristics of 14 Patients With HIT-Associated Thrombosis
Gender, Age at Admission | Admission Diagnosis | Site of Thrombosis | Hep Exp | Previous Hep | Platelet Decline (%) | Platelet-Nadir × 109/L | HPF4-AB |
---|---|---|---|---|---|---|---|
Female, newborn | Open heart surgery | Left common iliacal artery | 6 | No | 51 | 191 | 153 |
Female, 6 mo | Open heart surgery | Right femoral artery; vena innominata | 5 | Yes | 88 | 46 | 134 |
Male, 10 mo | Open heart surgery | Superior vena cava | 10 | Yes | 55 | 46 | 112 |
Female, 15 mo | Open heart surgery | Right subclavian vein | 16 | Yes | 65 | 123 | 104 |
Male, 13 y | Embolisation of aorto-pulmonary shunts after lung bleeding | Left subclavian vein; inferior vena cava; left and right external iliac veins | 19 | No | 67 | 55 | 135 |
Male, 13 y | Meningococcal sepsis | Left external iliac vein | 10 | No | 73 | 27 | 101 |
Male, newborn | Open heart surgery | Right external iliac vein | 15 | No | 52 | 55 | 68 |
Male, 3 mo | Open heart surgery | Right femoral artery | 7 | Yes | 56 | 37 | 54 |
Male, newborn | Open heart surgery | Right femoral artery; right femoral vein; superior vena cava; right renal vein | 9 | No | 78 | 29 | 43 |
Female, newborn | Open heart surgery | Right subclavian vein | 16 | No | 60 | 60 | 58 |
Male, 3 mo | Abdominal surgery | Inferior vena cava; left femoral vein | 45 | No | 77 | 43 | 57 |
Male, 7 mo | Open heart surgery | Left external iliac vein | 5 | Yes | 73 | 43 | 26 |
Male, 17 mo | Open heart surgery | Right internal iugular vein | 25 | Yes | 61 | 80 | 83 |
Female, 4 y | Open heart surgery | Left external iugular vein | 8 | No | 70 | 93 | 38 |
Hep Exp indicates heparin exposure before diagnosis (days); Previous Hep, heparin administration during preceding 6 months; HPF4-AB, percentage of adult cutoff value of ELISA optical density.