TABLE 5.

Clinically Unsuspected CAH Patients: Neonatal Screening Versus Case Surveillance (Median [Range])

Clinically Unsuspected CAH PatientsSignificance*
ScreeningNo Screening
Number males/females6/310/2
Day of admission7 (2–9)15 (6–95)P < .001
Day at start therapy9** (7–31)19*** (10–115)P < .002
Sodium mmol/L134 (129–138)119 (101–137)P < .001
Serum sodium (%) <135 mmol/L5590
Potassium mmol/L6.1 (5.3–8.1)8.2 (4.9–9.7)P < .006
Serum potassium (%) ≥5.5 mmol/L9090
  • * Mann-Whitney (2-tailed).

  • ** In 1 child, therapy was started at day 31, as the heel puncture was postponed to day 30, attributable to transfer between hospitals.

  • *** Start therapy at 115 days in a NSW female patient.