Table 4.

Sensitivity, Specificity, PPV, and NPV for ETCOc Greater Than the Population Mean at 30 ± 6 Hours of Life (Mean ± SD) for STB ≥95th Percentile of the Total Study Population

Test (ETCOc)Disease
Positive (120)Negative (1250)
PositiveTrue Positive (TP) (92)False Positive (FP) (615)TP + FP (707)PPV 92/707 = 13.0%
NegativeFalse Negative (FN) (28) True Negative(TN) (635) FN + TN (663)NPV 635/663 = 95.8%
TP + FN (120)FP + TN (1250)
Sensitivity 92/120 = 76.7% Specificity 635/1250 = 50.8%
• Sensitivity = TP/TP + FN, the probability of the test finding disease among those who have the disease or the proportion of those with the disease who have a positive test result.

Specificity = TN/TN + FP, the probability of the test finding no disease among those who do not have the disease or the proportion of those free of the disease who have a negative test result.

PPV = TP/TP + FP, the percentage of people with a positive test result who actually have the disease.

NPV = TN/FN + TN, the percentage of people with a negative test result who do not have the disease.