Table 3.

Multivariate Analysis* of the Effect of PIs on Growth

Growth EndpointOverall PI Effect
(SE)
PValueRitonavir Effect (SE)P ValueIndinavir Effect (SE)P ValueNelfinavir Effect

(SE)
P Value
Height zscore0.17 (0.10).100.30 (0.13).024−0.07 (0.13).590.08 (0.11).48
Weight zscore0.46 (0.11)<.0010.41 (0.12).0010.42 (0.21).0490.45 (0.11)<.001
Weight-for-height zscore0.49 (0.20).0160.31 (0.31).320.88 (0.39).0230.53 (0.18).003
AMC percentile11.5 (3.8).0038.2 (5.7).1512.8 (4.7).00612.1 (3.6).001
TSF percentile1.9 (4.0).63−2.8 (5.4).60−1.4 (5.7).805.3 (4.9).28
  • * Model was adjusted for sex, age, Tanner stage, race, route of infection, CDC stage, HIV RNA PCR, CD4 z score, time with HIV infection, Megace use, NRTI, NNRTI, and energy intake.