Table 1.

Study Population

PlaceboMetformin
Age (y)15.4 ± 0.514.4 ± 0.6
Gender (M/F)8/73/11
Ethinicity (white/black)7/89/5
BMI (kg/M2)38.7 ± 1.341.5 ± 0.9*
Glucose (fasting, mg%)77.2 ± 3.084.9 ± 4.5
Insulin (fasting, μU/mL)28.0 ± 3.231.5 ± 3.4
HbA1c (%)5.5 ± 0.15.6 ± 0.1
Leptin (ng/mL)
Males28.0 ± 3.330.2 ± 2.0
Females47.7 ± 7.4** 57.0 ± 5.4**
  • Values are mean ± standard error.

  • * P < .05, metformin versus placebo.

  • ** P < .02, females versus males.