Table 2.

Clinical Variables

FactorDay(s)Fluconazole-Treated
(n = 53)
Placebo-Treated (n = 50)P Value
Length of antibiotics02 (3.8)2 (4).770
1–35 (9.4)6 (12)
4–77 (13.2)3 (6)
8–1416 (30)18 (36)
>1423 (43)21 (42)
Length of methylxanthine (theophylline, caffeine)07 (13.2)5 (10).868
1–146 (11.3)4 (8)
15–286 (11.3)7 (14)
>2834 (64.2)34 (68)
Length of systemic steroids029 (54.7)33 (66).416
1–1419 (35.9)12 (24)
>145 (9.4)5 (10)
Length of intubation09 (17)6 (12).081
1–1418 (34)29 (58)
15–2814 (26.4)6 (12)
>2812 (22.6)9 (18)
Length of parenteral nutrition 0–1415 (28.3)20 (40).210
>1438 (71.7)30 (60)
Length of Intralipid 0–1418 (34)21 (42).401
>1435 (66)29 (58)
Length of central line use (PICC, UAC, UVC, Broviak)08 (15.1)8 (16).762
1–1419 (35.8)21 (42)
>1426 (49.1)21 (42)
Length required to regain birth weight1–727 (50.9)14 (31.1).126
8–1411 (20.8)15 (33.3)
>1415 (28.3)16 (35.6)
DOL initially fed1–540 (76.9)38 (80.9).633
>512 (23.1)9 (19.1)
DOL initially fed1–540 (76.9)38 (80.9).633
>512 (23.1)9 (19.1)
DOL when at full enteral feeds 5–1414 (28.5)17 (38.6).260
15–2116 (32.7)8 (18.2)
>2119 (38.8)19 (43.2)
Length of oxygen therapy 0–2818 (34)23 (46).212
>2835 (66)27 (54)
Length of hospitalization<281 (2.1)4 (10.3).265
28–5619 (39.6)14 (35.9)
>5628 (58.3)21 (53.8)
  • PICC indicates peripherally inserted central catheter; UAC, umbilical arterial catheter; UVC, umbilical venous line.

  • * All values reflect n (%).