Table 3.

Secondary Outcomes: Lipoproteins, Lipids, and BMI

InterventionUsual CareAdjusted Difference*PValue
nMean(SD)nMean(SD)Difference(95% CI)
Total Cholesterol, mg/dL [mmol/L]
Baseline334200.0(14.6)329200.0(14.6)
[5.17][.38][5.17][.38]
Year 1315191.4(20.9)303197.4(21.4)−6.1(−9.1, −3.2)<.001
[4.95][.54][5.10][.55][−.16][−.23, −.08]
Year 3320183.3(21.5)303186.4(22.3)−3.3(−6.4, −0.2).04
[4.74][.56][4.82][.58][−.09][−.17, −.00]
Year 5268175.6(22.4)254177.9(25.7)−2.6(−6.3, 1.2).18
[4.54][.58][4.60][.67][−.07][−.16, .03]
Last visit283179.4(24.1)265180.1(26.3)−1.1(−5.0, 2.8).59
[4.64][.62][4.66][.68][−.03][−.13, .07]
HDL-C, mg/dL [mmol/L]
Baseline334 57.1(10.7)329 57.0(11.0)
[1.48][.28][1.47][.29]
Year 1315 55.5(11.1)303 56.8(11.1)−1.3(−2.4, −.2).03
[1.44][.29][1.47][.29][−.03][−.06, .00]
Year 3320 52.7(10.0)303 52.6(10.3)−0.2(−1.2, 0.9).75
[1.36][.26][1.36][.27] [.00][−.03, .02]
Year 5268 50.5(11.2)254 51.1(10.2) −.8(−2.2, .6).28
[1.31][.29][1.32][.26][−.02][−.06, .02]
Last visit283 49.8(11.1)265 49.3(9.6).3(−1.0, 1.7).62
[1.29][.29][1.27][.25] [.01][−.03, .04]
Triglycerides, mg/dL [mmol/L]
Baseline334 80.1(28.8)329 80.9(28.0)
[.90][.33][.91][.32]
Year 1315 86.2(38.7)303 87.1(39.4) −.5(−5.8, 4.7).84
[.97][.44][.98][.44][−.01][−.07, .05]
Year 3320 99.5(46.0)303 98.9(44.8) 1.5(−4.5, 7.5).62
[1.12][.52][1.12][.51] [.02][−.05, .08]
Year 5268100.3(58.3)254 94.5(46.8) 6.6(−1.8, 15.0).12
[1.13][.66][1.07][.53] [.07][−.02, 0.17]
Last visit283100.5(51.2)265 97.0(44.0) 3.4(−4.1, 10.9).3
[1.13][.58][1.10][.50] [.04][−.05, .12]
Body mass index, kg/m2
Baseline334 17.5 (2.3)329 17.6 (2.4)
Year 1313 18.2 (2.7)307 18.5 (3.0) −.2(−.3, 0).03
Year 3317 19.9 (3.3)305 20.1 (3.4)0(−.3, .2).39
Year 5276 21.7 (3.8)265 21.7 (3.7).1(−.3, .5).67
Last visit293 22.9 (3.8)283 23.0 (4.1) −.1(−.5, .4).39
  • SD indicates standard deviation.

  • * Adjusted for baseline value, sex, and age at last visit (for last visit only).