Table 3.

Demographic, Nutritional, and Clinical Characteristics at the Time of Diagnosis of CF in Patients Without MI

CharacteristicScreened
Group
(n = 56)
Control
Group
(n = 48)
P
Value
Age at diagnosis, wk<.001
 Mean (SD)13 (37)107 (117)
 Median (range)7 (4–281)28 (3–372)
Sex, no. (%)1.000
 Male35 (63)30 (63)
 Female21 (37)20 (37)
Center, no. (%).698
 Madison28 (50)26 (54)
 Milwaukee28 (50)22 (46)
Genotype, no. (%)<.001
 ΔF508/ΔF50833 (59)22 (47)
 ΔF508/other*23 (41)19 (34)
 Other/other*0 9 (19)
Pancreatic status, no. (%)<.001
 Sufficiency (probable or established)5 (9)15 (33)
 Insufficiency (probable or established)49 (91)30 (67)
Length or height
 Percentile (SD)44 (28)26 (27)<.001
z score (SD)−.21 (1.0)−1.0 (1.3)<.001
Weight
 Percentile (SD)35 (28)24 (26).027
z score (SD)−.5 (1.1)−1.0 (1.1).027
Head circumference
 Percentile52 (28)32 (24).003
(n = 46)(n = 29)
Plasma vitamin A—μg/dL (SD)28 (16)36 (20).029
Plasma vitamin E—μg/dL (SD)471 (375)520 (450).733
  • * Other CFTR alleles included G542X, R117H, G551D, R553X, N1303K, and W1282X. The distribution of identified CFTR mutations was similar to that of Wisconsin16 and the US population3 of CF patients (ΔF508 [70.1%], G542X [2.3%], R117H [1.6%], G551D [1.3%], R553X [1.3%], and W1282 [.3%]).