Table 1.

Viral and Immunologic Response in Responders and Nonresponders

Responders
(≥2 Log Change in VL)
Nonresponders
(<2 Log Change in VL)
P
Value
Number107
Median baseline log VL before GT (range)5.5 (4.75–5.87)5.24 (4.80–6.67)1
Median log VL change after GT (range)−3.2 (2.1–3.5)−1.27 (.63–1.6).0008
Undetectable VL (%)8 (80%)0 (0%).02
Median baseline CD4% before GT (range)16% (1–46)23% (1–50).6
Median CD4% change after GT (range)+7% (2%–28.5%)+10% (3%–23%).2
PI naive at time of GT (%)5 (50%)4 (57%).9
Therapy change to double PI regimen (%)4 (40%)3 (42%).4
Median time of medication change in relation
to GT in mo (range)
.8 mo after insertion
(0–6 mo after insertion)
3.2 mo before insertion
(1–8 mo before insertion)
.005
  • PI indicates protease inhibitor.

  • * <400 copies/mL.