Table 2.

Rates of Large Swelling Reactions to Booster Doses of Various DTaP Vaccines Among Children Given the Same Vaccine for All Doses

Manufacturer
(Number of Pertussis Components)
Postdose 4Postdose 5
Subjects nSwelling >50 mm n(%)*Entire Thigh Swelling n (%)SubjectsnSwelling >50 mm n (%)*
Pasteur Mérieur (2)707 (10.0)4 (5.7)183 (16.7)
Biocine Sclavo (3)713 (4.2)3 (4.2)222 (9.1)
Smith-Kline Beecham Biologicals (3)765 (6.6)3 (3.9)226 (27.3)
Connaught Laboratories, Canada (5)754 (5.3)2 (2.7)121 (8.3)
Swiss Serum Vaccine Institute (1)816 (7.5)2 (2.5)0
Smith-Kline Beecham Biologicals (2)1284 (3.1)3 (2.3)0
Porton Products (4)732 (2.7)1 (1.4)0
Connaught Laboratories, Canada (4)743 (4.1)1 (1.4)0
Michigan Department of Public Health (2)863 (3.5)1 (1.2)0
Biocine Sclavo (1)641 (1.6)00
Connaught Laboratories, United States (2)843 (3.6)0180
Lederle-Praxis (4)1334 (2.7)0293 (10.3)
Lederle DtwP162 (12.5)1 (6.3)40
  • * Excludes children with entire limb swelling.