Table 2.

Respiratory Outcomes

Hypercapnia GroupNC GroupP ValueRR (95% CI)
Assisted ventilation (d)* 2.5 (1.5–11.5)9.5 (2.0–22.5).17
Supplemental oxygen (d)* 15 (4–53)32 (17–50).34
BPD (%)43 (9/21)64 (14/22).290.67 (0.35, 1.29)
Oxygen at 36 weeks (%)10 (2/21)9 (2/22)1.01.05 (0.11, 10.10)
Air leaks (%)8 (2/24)16 (4/25).670.52 (0.07, 3.08)
Reintubation rate
 Within 24 h (%)17 (4/24)28 (7/25).540.60 (0.16, 2.0)
 Any time (%)67 (16/24)48 (12/25).301.39 (0.80, 2.36)
 Reintubations for apnea (%)21 (5/24)12 (3/25).461.74 (0.40, 8.74)
Postnatal steroids (%)12 (3/24)24 (6/25).460.52 (0.11, 2.11)
 One course4 (1/24)12 (3/25).610.35 (0.01, 3.55)
 More than one course8 (2/24)12 (3/25)1.00.69 (0.08, 4.86)
Surfactant (doses)* 2 (1–3)3 (2–3).21
Extubated to NCPAP (%)25 (6/24)40 (10/25).270.63 (0.23, 1.59)
  • CPAP indicates continuous positive airway pressure. BPD and oxygen at 36 weeks are reported for survivors only.

    Relative risk (RR) was calculated for the dichotomous outcome measures.

  • * Data given as median (25th–75th percentile).