Table 1.

Demographic Data and Prerandomization Ventilator Settings and Blood Gas Values

Hypercapnia Group (n = 24)NC Group (n = 25)P Value
Birth weight (g)852  ± 156856  ± 173.92
Gestational age (wk)26  ± 126  ± 2.43
Entry age (h)8.5 (5.5–14)    9 (5–12)    .81
Black race (%)6256.86
Female (%)5456.89
Twin gestation (%)21161.0
Antenatal steroids (%)7152.29
Full course steroids (%)2936.83
Cesarean section (%)6256.86
Chorioamnionitis (%)12121.0
Apgar 1 (median) 3 3.90
Apgar 5 (median) 7 6.56
Prerandomization settings
 Peak inspiratory pressure (cm H2O)20 (18–23)      20 (17–23)    .98
 Mean airway pressure (cm H2O)7 (6–9)         8 (6–9)     .59
 Rate/minute30 (22–42)       30 (26–35)      .87
 Fio 2 0.35 (0.27–0.48)  0.50 (0.25–0.66).44
Prerandomization gases
 pH7.38  ± 0.087.37  ± 0.07.55
 Paco 2 (mm Hg)37  ± 1036  ± 8.86
 Pao 2 (mm Hg)57.5 (50–80)     53 (43–67)     .23
 Oxygenation index4.0 (2.9–6.3)    5.3 (2.7–10.9) .50
 Arterial to alveolar oxygen ratio0.31  ± 0.180.29  ± 0.19.69
  • Data given as median (25th–75th percentile) for nonparametric tests and as mean ± SD for parametric tests.