Table 1.

Distribution of UGT1A1 Genotypes and Frequencies of Allele With Mutated Codon 71 (G71R) in the Control and Hyperbilirubinemic Groups

Genotype DistributionAllele Frequency
nCodon 71 Mutation (G71R)
NormalHetero*HomonAGA (G71R)
Control group50351411000.16
Hyperbilirubinemic group2511113500.34
  • Missense mutation of codon 71, from GGA to AGA (G71R):

  • * heterozygous for AGA;

  • homozygous for AGA. Significant difference from control group:

  • χ2 = 5.56, P < .025.