Table 2.

Incidence of Grade 3 or Greater Toxicities

Abnormal FindingTotal
(N = 108)
Arm 1
(N = 49)
Arm 2
(N = 30)
Arm 3
(N = 29)
Any hematologic abnormality4  (4)04  (13)0
 Anemia1  (1)01  (3)0
 Neutropenia2  (2)02  (7)0
 Thrombocytopenia1  (1)01  (3)0
Any chemistry abnormality2  (2)1  (2)1  (3)0
 Creatine phosphokinase1  (1)1  (2)00
 Amylase/lipase1  (1)01  (3)0
Any clinical sign or symptom15  (14)4  (8)7  (23)4  (14)
  • Arm 1: d4T plus ddl, previous d4T; arm 2: d4T, previous ZDV; arm 3: d4T plus ddl, previous ZDV.

    Numbers in parentheses indicate percent of patients assigned to that treatment.