Table 3.

Multivariate Analysis of NF (Model #1, Ibuprofen Use; Model #2, Acetaminophen Use)

Predictors of NFOR (95% CI)
Model #1
 Ibuprofen use
  yes10.2 (1.3, 79.5)
  no1.0
 GAS isolation
  yes19.8 (2.9, 137.1)
  no1.0
 Age years (continuous).8 (.6, 1.2)
 Gender
  female.2 (.0, 1.2)
  male1.0
Model #2
 Acetaminophen use
  yes.6 (.1, 3.9)
  no1.0
 GAS isolation
  yes13.0 (2.5, 67.0)
  no1.0
 Age years (continuous).9 (.7, 1.3)
 Gender
  female.3 (.1, 1.2)
  male1.0
  • Abbreviations: NF, necrotizing fasciitis; OR, odds ratio; CI, confidence interval; GAS, group A streptococcus.