Table 2.

Suggested Information to Gather for Study of HHE Risk Factors*

Information included in case definition (see Table 1)
 Including degree of limpness, hyporesponsiveness, and pallor or cyanosis
All vaccines administered
Posture and activity before episode
Peak temperature before and during episode, vital signs
Antipyretic administered before HHE? If so, note number of hours prior
Excessive crying or abnormal crying before HHE?
Vomiting before, during, or after HHE?
Medical and obstetric history
Developmental level before HHE event
Family history of syncope, seizures, or migraine, or HHE
Results of physical examination and laboratory/diagnostic testing
Description of method of HHE ascertainment
  • * Not an exhaustive list