Table 3.

Temperature by Treatment Group

Ibuprofen GroupPlacebo Group
All fever episodes271284
 At fever onset39.1  (38.7–39.4)39.0  (38.7–39.3)
 At 6 (±2) hours after fever onset38.2  (37.3–39.0)38.9  (38.2–39.3)
Fever episodes with recurrence
 Intention-to-treat analysis 31 36
 At fever onset39.0  (38.7–39.7)39.4  (38.8–39.7)
 At febrile seizure recurrence39.9  (39.0–40.3)39.6  (39.1–40.0)
 Per-protocol analysis 13 17
 At fever onset39.0  (38.6–39.1)39.5  (38.7–39.8)
 At febrile seizure recurrence40.1  (39.9–40.4)40.0  (39.4–40.3)
  • Note: Median temperatures, Celsius (25th–75th percentiles).