Table 1.

Underlying Illnesses or Conditions in Patients From Eight Children's Hospitals With Systemic Pneumococcal Infections From September 1993 to August 1996

Underlying IllnessNumber*
Central nervous system disorder65
Heart disease61
Renal disease44
Leukemia37
Human immunodeficiency virus35
Hemoglobinopathy31
Genetic disorder26
Other malignancy25
Asplenia16
Cystic fibrosis7
  • * For episodes, not patients; 1291 total episodes.

  • Asplenia associated with the following conditions: congenital heart disease (n = 8), none (n = 3), Hodgkin's disease treatment (n = 2), leukemia (n = 1), hemoglobinopathy (n = 1), and genetic disorder (n = 1).