Table 1.

Literature Reports of Aortic Dilation, Dissection, or Rupture in Turner Syndrome (N = 67)

PatientAuthorAgeCVMHypertensionLocation of
Dilation
Severity of
Dilation
SurgeryStatus
 1Salgado* 45Desc aortaDissectionAttemptedDied
 2Anabtawi et al* 34BAV, COAModerateDistal to COADissectionAttemptedDied
 3Kostich and Opitz* 35BAV, AS, ARAsc aortaDissectionAttemptedDied
 4Youker and Roe* 19BAV, AS, AR, COAMildAsc aortaDissectionResection of COA and aneurysm, AV replacementAlive
 5Strader et al* 15BAV, COAModerateAsc aortaDissectionDied
 6Lippe and Kogut* 4COAModerateAsc aortaDissectionDied
 7Lippe and Kogut* 20MildAsc aortaDissectionDied
 8Jeresaty et al* 54Pseudo-COAModerateAsc aorta & distal to COADissectionAlive
 9Wendel32Pseudo-COA, ASMildAsc through desc aortaSevereDied
10Guerin17Pseudo-COA, ASAsc aortaDissectionResection of aneurysm, AV commisurotomyAlive
11Miller64ModerateDesc aortaDissectionAlive
12Bargman et al18(AR)Asc aortaSevereAlive
13Edwards et al* 27BAVNSAsc aortaDissectionDied
14Asch* 8BAV, AS, AR, pseudo-COAAsc and desc aortaDissectionResection of aneurysmAlive
15Lie* 37BAV, AS, ARModerateAsc and desc aortaDissectionDied
16Slater et al* 40BAV, ASAsc aortaDissectionDied
17Price and Wilson* 29Asc and desc aortaDissectionDied
18Price and Wilson* 38(AR)MildAsc aortaDissectionDied
19Price and Wilson; Price et al* 30NSAsc aortaDissectionDied
20Goldberg et al* 28AS, ARAsc aortaDissectionRepair of dissection, AV replacementAlive
21Lin et al28BAV, AS, ARAsc aortaDissectionDied
22Lin et al19COA, BAV, AS, ARMildAsc aortaDissectionCOA repair; repair of dissection, AV and root replacementAlive
23Lin et al23Sinus of ValsalvaMildAlive
24Lin et al24BAVMildSinus of ValsalvaModerateAlive
25Lin et al14BAV, AS, ARAsc aortaMildAlive
26Lin et al16BAV, ARAsc aortaMildAlive
27–34Allen et alNSBAV (4/8)NSAsc aortaNSNSAlive
(8 pts)(11–26)
35Boxer et alNSNSNSNSNSNSNS
36Hata10NSNSAsc aortaDissectionAttemptedDied
37Hata49NSNSNSDissectionAttemptedDied
38Mori14Pseudo-COA, BAV+Asc aortaModerate aneurysmAlive
39Price et al39NSNSDissectionNSDied
40Price et al38NSArch and desc aortaDissectionNSDied
41Price et al18COANSNSDissectionNSDied
42Martin5COA, ASSite of COA repairMildCOA repairAlive
43Subramaniam30(AR)+NSSinus of Valsalva aneurysmSevereResection of aneurysm and AV replacementAlive
44Vesin and Chudanova23BAV, AR, MRNSAsc aorta and archDissectionAlive
45Dawson-Falk et alNSBAVNSAsc aortaNSNSAlive
46Dawson-Falk et alNSBAV, ASNSAsc aortaNSNSAlive
47Dawson-Falk et alNSNSAsc aortaNSNSAlive
48Dawson-Falk et alNSNSAsc aortaNSNSAlive
49Dawson-Falk et alNSNSAsc aortaNSNSAlive
50Apostolopoulos36BAV, ASAsc aorta and archModerateAlive
51Cecchi27(AR)ModerateAsc aortaDissectionResection of aneurysm, AV replacementAlive
52Ohuchi et al27COA, AS, AR+Asc aortaBypass graft of aneurysm, AV replacementAlive
53Ota et al14BAV, COAMildAsc aortaDissectionBypass graft asc to desc aorta; AV replacementDied
54Ota et al18COAMildCOA site desc aortaRupture of aneurysmCOA repair; redo COA repair; attempted aneurysm repairDied
55Pollak43BAV, AR, single LCA“Labile”Asc and desc aortaDissectionResection of aneurysm, AV replacementAlive
56Rubin19Asc aortaDissectionDied
57Lippe34MildAsc aortaDissectionDied
58Akimoto42MildDesc aortaDissectionRepair of dissectionAlive
59Kido et al36ModerateAsc aortaDissectionDied
60Bartlema27Desc aortaDissectionAlive
61Cohara et al25BAV, ARAsc aortaDissectionResection of aneurysm, AV replacementAlive
62Hochberg48BAV+MildAsc aortaDissectionDied
63Imamura19COA, BAV, AS, ARAsc aortaDissectionBalloon angioplasty of COA, resection of aneurysm, AV replacementAlive
64Kusaba23COASevereAsc aorta, desc aortaSevereCOA repair, resection of aneurysmAlive
65Buheitel et al16COA, ASAsc aortaDissectionCOA repairDied
66Bueheitel et al19ASSevereAsc and desc aortaDissectionAttemptedDied
67NagelNS+NSAsc aortaDissectionDied
68NagelNSAsc aortaDissectionDied
  • * As summarized in Lin et al.4

    Abbreviations: Asc, ascending; Desc, descending; LCA, left coronary artery; NS, not stated.