Table 4.

PPHN Major Sequelae

PPHN Sequelae (Total Enrollment)Control
(n = 41)
Nitric Oxide
(n = 114)
P
Value
At least one sequelae (%)* 23/41 (56)52/104 (50)0.51
Death <28 d (%)1/41 (2)9/113 (8)0.22
Neurologic sequelae (%)* 10/39 (26)23/97 (24) 0.81
Bronchopulmonary dysplasia/reactive airway disease (%)*  5/40 (13)15/103 (15)0.75
ECMO rescue (%)14/41 (34)25/114 (22)0.12
  • * Some 28-day follow-up not obtained.

  • Cochran-Mantel-Haenszel test.