Table 3.

Duration of Treatment*

Treatment GasControl Group
(n = 41)
Nitric Oxide Groups
(n = 114)
PValue
Treatment gas (h)
 All patients68  ± 7458  ± 580.99
 Until success: weaning criteria 107  ± 6981  ± 590.13
 Until failure: cardiopulmonary instability 10  ± 1110  ± 130.58
Time to ECMO (h)22  ± 1542  ± 440.24
Duration of ECMO (h)103  ± 32129  ± 630.26
Mechanical ventilation (h)199  ± 111220  ± 1770.94
Supplemental oxygen (h)
 All patients155  ± 164129  ± 1360.47
 Success: weaning criteria 69  ± 6097  ± 710.13
 Failure: cardiopulmonary instability 260  ± 224154  ± 1630.08
Hospitalization (h)§ 628  ± 482535  ± 2670.45
  • Values are mean ± SD.

  • * Time (hours) starts at initiation of treatment gas.

  • Pao 2 ≥60 Torr when Fio 2 <0.6, mean airway pressure <10 cm H2O.

  • Study definitions of hypoxemia, hypotension, need for other rescue.

  • § Until 8 am day of discharge.

  • Wilcoxon rank sum test.