Table 4.

A Summary of Side Effects Following Early Postnatal Dexamethasone Therapy

Age (days)
235710142128
Systolic blood pressureC57  ± 1356  ± 1062  ± 1464  ± 1463  ± 1167  ± 1270  ± 1672  ± 15
(mm Hg)D58  ± 1660  ± 12**67  ± 1771  ± 15**69  ± 12**74  ± 16**77  ± 1673  ± 15
Diastolic blood pressureC35  ± 1034  ± 738  ± 1141  ± 1138  ± 940  ± 1043  ± 1244  ± 11
(mm Hg)D36  ± 1137  ± 9**42  ± 1246  ± 13**44  ± 11**46  ± 12**49  ± 1143  ± 11
GlucoseC129  ± 84133  ± 95123  ± 63125  ± 75119  ± 84117  ± 90101  ± 4790  ± 34
(mg %)D151  ± 92**146  ± 85**150  ± 84**151  ± 99**138  ± 80**122  ± 66120  ± 5693  ± 44
Blood urea nitrogenC24  ± 1319  ± 1118  ± 1215  ± 1314  ± 119  ± 77  ± 66  ± 4
(mg %)D29  ± 12*31  ± 13**36  ± 15**33  ± 15**24  ± 17**19  ± 17**11  ± 810  ± 8
Serum potassiumC4.9  ± 1.34.7  ± 1.24.5  ± 1.14.6  ± 0.94.7  ± 0.84.6  ± 0.74.6  ± 0.84.7  ± 0.8
(meq/L)D5.6  ± 1.1*5.3  ± 1.0*5.1  ± 1.8*4.9  ± 0.94.9  ± 0.94.9  ± 1.14.9  ± 0.74.8  ± 0.8
OsmolalityC276  ± 26285  ± 29278  ± 29275  ± 25274  ± 25279  ± 14275  ± 23275  ± 11
(mosm)D285  ± 24292  ± 31285  ± 39286  ± 34*287  ± 16*280  ± 24281  ± 9275  ± 13
EchoC0.20  ± 0.060.21  ± 0.060.25  ± 0.080.29  ± 0.080.25  ± 0.110.29  ± 0.11
LVFW/LVCD0.24  ± 0.150.27  ± 0.120.35  ± 0.17*0.30  ± 0.120.34  ± 0.11*0.26  ± 0.09
FEPC39  ± 2743  ± 3235  ± 2725  ± 2123  ± 1754  ± 5130  ± 28
(%)D57  ± 27*60  ± 27*39  ± 2731  ± 2235  ± 3444  ± 2027  ± 26
PTHC98  ± 5599  ± 5382  ± 8092  ± 9157  ± 2957  ± 4555  ± 31
(pg/mL)D233  ± 182*165  ± 125*131  ± 92*111  ± 64117  ± 8262  ± 3473  ± 25
  • Abbreviations: C, control; D, dexamethasone treated; LVFW/LVC, left ventricle free wall/left ventricle chamber; FEp, urinary fractional excretion of phosphate; PTH, parathyroid hormone.

  • * P < .05.

  • ** P < .01 (C vs D).