Table 8.

Intraventricular Hemorrhage (IVH) and Periventricular Leukomalacia (PVL)

Exosurf
(n = 422)
%
Infasurf
(n = 431)
%
Risk Ratio*
(Infasurf/Exosurf)
95%
Confidence
Interval
IVH
 None70.161.0
 Grade 111.414.6
 Grade 210.212.5
 Grade 33.15.6
 Grade 45.26.3
Any IVH29.939.01.3(1.08, 1.57)
Severe IVH8.311.81.41(0.94, 2.09)
PVL3.36.52.03(1.09, 3.80)
Severe IVH or PVL11.417.61.54(1.11, 2.14)
  • * Adjusted for center and birth weight subgroups.

  • P = .015 (Mantel-Hantzel χ2).