Table 6.

Air Leak Complications of RDS

Type of Air LeakExosurf
(n = 423)
Infasurf
(n = 423)
Risk Ratio*
(Infasurf/Exosurf)
95% Confidence Interval
n(%)n(%)
Pneumothorax (≤7 day)26(6)16(4)0.60(0.32, 1.09)
Pulmonary interstitial emphysema (≤7 d)48(11)20(5)0.40(0.24, 0.66)
Total early air leak (≤7 d)60(14)34(8)0.55(0.37, 0.81)
Total late air leak (>7 d)7(2)8(2)0.96(0.35, 2.69)
Total air leak65(15)42(10)0.62(0.43, 0.88)
  • * Adjusted for center and birth weight subgroups.