Table 3.

Surfactant Treatment Profile

DescriptorExosurf
(n = 423)
Infasurf
(n = 423)
P Value
No. (%)
Number of doses of assigned surfactant.88
 06  (1)2  (1)
 149  (12)56  (13)
 242  (10)38  (9)
 3326  (77)326  (77)
 >30  (0)1  (1)
At 72 h
Number of infants treated with crossover surfactant24  (6)4  (1).0001
Withdrawn from study18  (4)11  (3).26
Crossover treatment and/or withdrawn from study41  (10)15  (4).0004
Mean ± SE
Age at first dose (min)15.6 ± 0.813.0 ± 0.4.24*
Age at second dose (h)12.4 ± 0.112.5 ± 0.1.19
Age at third dose (h)24.7 ± 0.124.9 ± 0.2.32
Average number of doses 2.6 ± 0.0 2.6 ± 0.0.89
  • * Wilcoxon rank sum test.