Table 2.

Peripheral Blood Cell Responses of Septic and Neutropenic Neonates After Treatment With rhG-CSF Compared With Recovery of Cell Counts With Conventional Therapy

Type of CellsGCSF-Treated Group (n = 14)Conventionally Treated Group (n = 11)
Day 0Day 1Day 2Day 3Day 7–10Day 0Day 1Day 2Day 3Day 7–10
Lymphocytes3378  ± 6242876  ± 7703457  ± 9095017  ± 26736680  ± 1008*2311  ± 2942636  ± 8583229  ± 15232753  ± 8024666  ± 1475
Monocytes558  ± 1581742  ± 15291198  ± 1492096  ± 4504143  ± 1215*261  ± 931104  ± 5881338  ± 4732234  ± 11013357  ± 1326*
Bands188  ± 611831  ± 7542246  ± 1034*2431  ± 616*4727  ± 1908*205  ± 89636  ± 170661  ± 215624  ± 1311491  ± 849*
Polymorphonuclear neutrophils304  ± 902849  ± 10305555  ± 2079*6731  ± 2228*10 307  ± 2630*160  ± 77203  ± 92878  ± 3051414  ± 4025342  ± 988*
Absolute neutrophil count585  ± 1384431  ± 12817633  ± 188512 473  ± 2927*16 236  ± 3159*438  ± 152839  ± 1741540  ± 4422039  ± 3636833  ± 1605*
White blood cell count total4790  ± 81111 190  ± 2054*15 189  ± 2721*23 100  ± 4647*23 775  ± 13 052*3480  ± 5596083  ± 18577025  ± 36738175  ± 357916 175  ± 4262*
  • * P < .05 vs cell count value at baseline upon entry into protocol tested by 1-way analysis of variance with repeated measures followed by Dunnet's multirange test; mean ± SEM.