Table 2.

Risk of HUS by Selected Clinical Characteristics Beginning ≤3 Days After Diarrheal Illness Onset and by Laboratory Values Among Children Tested Within 3 Days of Diarrheal Illness Onset

FactorProportion of Patients With Factor Who Developed HUSProportion of Patients Without Factor Who Developed HUSRate Ratio (95% CI)P Value
Number/Total (%)Number/Total (%)
Vomiting22/127 (17)13/140 (9)1.9 (1.0–3.5).05
Bloody diarrhea29/213 (14)7/59 (12)1.1 (0.5–2.5).73
Fever11/56 (20)20/169 (12)1.8 (0.8–4.1).14
Hematocrit
 >39%10/70 (14)8/58 (14)1.0 (0.4–2.5).94
Platelets
 >310 000/μL10/59 (17)8/67 (12)1.4 (0.6–3.6).42
BUN
 >9 mg/dL7/64 (11)8/49 (16)0.7 (0.3–1.7).40
WBC count
 >10 500/μL15/63 (24)3/65 (5)5.2 (1.6–17.0)<.01
 ≥13 000/μL13/34 (38) 5/94 (5)7.2 (2.8–18.5)<.01
Segmented neutrophils
 >69%9/56 (16) 7/53 (13)1.2 (0.5–3.0).67
Any band forms11/57 (19) 5/52 (10)2.0 (0.7–5.4).15