TABLE 1

Quick Reference Guide for Blood Tests to Accurately Detect Type-Specific HSV Antibodies

Biokit HSV-2 Rapid Test (also sold as SureVue HSV-2 Rapid Test by Fisher HealthCare)BioPlex HSVCaptia ELISAEuroimmun Anti-HSV-1 and Anti-HSV-2 ELISAHerpeSelect HSV-1 ELISA and HerpeSelect HSV-2 ELISAHerpeSelect 1 and 2 Differentiation ImmunoblotLiaison HSV-2AtheNA MultiLyte
SupplierBiokit USABio-Rad LaboratoriesTrinity Biotech USAEuroimmun US LLCFocus DiagnosticsFocus DiagnosticsDiaSorin Inc.Inverness Medical
FDA approved19992009200420072000/2002200020082008
Antibodies detectedHSV-2 onlyHSV-1 or HSV-2 or bothHSV-1 or HSV-2 or bothHSV-1 or HSV-2HSV-1 or HSV-2 or bothHSV-1 and/or HSV-2HSV-1 or HSV-2HSV-1 and/or HSV-2
Best use of testPOC test to screen or test individuals >3 mo postexposureScreening or testing (high volume)Screening or testing pregnant women or STD clinic patients (moderate volume)Moderate volumeScreening or testing STD patients or pregnant women (moderate volume)Low volumeHigh volumeScreening or testing (moderate to high volume)
Collection methodFinger stick, whole blood, or serum in clinicBlood draw (sent to laboratory)Blood draw (sent to laboratory)Blood draw (sent to laboratory)Blood draw (sent to laboratory)Blood draw (sent to laboratory)Blood draw (sent to laboratory)Blood draw (sent to laboratory)
Test time10 min45 min∼2 h∼2 h∼2 h∼2 h35 min∼2 h
FDA approved for use during pregnancyYesYesYesYes
Test availabilityLimitedLimitedWidely availableWidely available
Web sitewww.biokitusa.comwww.bio-rad.comwww.trinitybiotech.comwww.euroimmunus.comwww.herpeselect.comwww.herpeselect.comwww.diasorin.comwww.invernessmedicalpd.com
For more information800-926-3353800-224-6723800-325-3424800-913-2022800-328-5669877-546-8633
  • FDA, US Food and Drug Administration; POC, point of care; STD, sexually transmitted disease. Adapted from http://www.ashastd.org/. Accessed August 5, 2010.