TABLE 1

Comparison of Characteristics of Neonates With and Without Trisomy 21 in a VLBW Cohort (BW <1500 g)

Trisomy 21 (N = 321)Non–Trisomy 21 (N = 98 759)P2 or t Test)
Male gender, % (n)52 (169)51 (49 972)Nonsignificant
Race/ethnicity, % (n)Nonsignificant
 White50 (159)47 (46 423)
 Black17 (53)26 (25 619)
 Asian4 (14)3 (3201)
 Other30 (95)24 (23 516)
GA, wk30.1 ± 2.528.1 ± 2.5<.01
BW, g1140 ± 2501040 ± 271<.01
Apgar score
 At 1 minute6.1 ± 2.25.4 ± 2.3<.001
 At 5 minutes7.8 ± 1.57.5 ± 1.7<.001
Chronological age at hospital discharge, wk10.0 ± 5.19.6 ± 4.9Nonsignificant
Fio2 >0.21, number of days32.5 ± 39.232.7 ± 32.9Nonsignificant
Receiving high-flow nasal cannula, number of days11.6 ± 19.69.7 ± 14.9<.05
Receiving ventilation, number of days10.2 ± 21.913.9 ± 24.7<.01
Receiving CPAP, number of days5.6 ± 10.88.8 ± 12.9<.01
  • Data are presented as means ± SDs unless otherwise indicated. CPAP, continuous positive airway pressure; Fio2, fraction of inspired oxygen.